The answer to this question is a resounding yes! Photoshop CS5 can absolutely run on Windows 10, without any issues whatsoever.
The main reason why people might think that Photoshop CS5 wouldn’t be able to run on Windows 10 is because Adobe has only officially released two versions of Photoshop that are compatible with Windows 10 – CS6 and CC. However, this doesn’t mean that other versions, like CS5, can’t run on the latest version of Windows.
In fact, Photoshop CS5 runs perfectly fine on Windows 10, and there are no known issues or compatibility problems. So if you’re still using CS5 and haven’t upgraded to a newer version yet, there’s no need to worry – you can still use it on Windows 10 without any problems.
So in conclusion, Yes, Photoshop CS5 can run on Windows 10 without any issues.